Study Highlights Sickle Cell Disease Prevalence in Socially Disadvantaged Areas

A recent study affirms that almost two-thirds of infants born with sickle cell disease (SCD) are from disadvantaged areas, characterized by crowded housing and limited transportation. The research, which dug into data from the Sickle Cell Data Collection Program, noted significant variations in the rates of SCD births in socially vulnerable areas across different states.

SCD Births and Social Vulnerability

The study was presented at the annual meeting of the American Society of Hematology, underscoring the intricate needs of children with SCD and their families. It suggests that public health initiatives should be directed towards areas with higher social vulnerability to improve access to care. The study also pinpoints the underutilization of effective, evidence-based treatments such as antibiotics and hydroxyurea, despite their proven effectiveness in alleviating SCD symptoms.

SCD Predominantly Found in Black Non-Hispanic Infants

SCD is predominantly found in Black non-Hispanic infants, with 90% of SCD births belonging to this demographic, and 57% of these children have sickle cell anemia, the most severe form of SCD. Sarah Reeves, Ph.D., an epidemiologist from the University of Michigan, illuminates the hurdles faced by individuals with SCD in accessing high-quality care, especially those from disadvantaged backgrounds.

Higher Rates of SCD Births Correlate with Higher SVI Scores

The researchers also utilized the CDC's Social Vulnerability Index (SVI) to analyze county-level data on social vulnerability, revealing that, except for Colorado, higher rates of SCD births correlate with higher SVI scores. Newborn screening for SCD, which can lead to early preventive treatments, varies across the country, and the study advocates for improved screening and treatment practices. Additional research by the team shows the alarming underuse of essential health services like stroke screening, antibiotics, and hydroxyurea in the national SCD population.